About

Podophyllum hexandrum, also known as Bankakari, is a perennial herb native to the Himalayan region, where it grows in cool and moist habitats. The plant features large, palmate leaves, with a single stem arising from a thick rhizome, and produces pink or white flowers followed by small red fruit. Bankakari is highly valued in traditional medicine for its therapeutic uses, particularly for treating skin ailments, liver disorders, and cancer. It contains podophyllotoxin, an important compound used in pharmaceutical applications, especially for antiviral and anticancer treatments. Despite its benefits, Podophyllum hexandrum is an endangered species due to unsustainable harvesting practices. Conservation initiatives are vital for its survival, focusing on controlled cultivation and promoting sustainable field collection practices.

Taxonomy & Ayurvedic Name

• Podophyllum hexandrum, commonly known as Bankakari, belongs to the kingdom Plantae and is classified within the division Angiosperms, the class Eudicots, and the order Ranunculales. It is a member of the family Berberidaceae, which includes various herbs and shrubs.
• In Ayurveda, this plant is referred to as Bankakari, also known by the name Papra, highlighting its traditional significance in herbal medicine.

Morphological Structuring

• Plant Type: Herbaceous perennial.
• Leaves: Large, palmate, deeply lobed, and arranged in a rosette pattern.
• Stem: Single, erect stem growing up to 50 cm in height.
• Flowers: Solitary, pink or white flowers, blooming in late spring.
• Fruit: Small, oval, red berries that are toxic when unripe.
• Rhizome: Thick, creeping rhizome used in medicinal preparations.

Health Benefits

• Anticancer: Contains podophyllotoxin, which is used in cancer treatments.
• Antiviral: Effective against certain viral infections, including genital warts.
• Liver Health: Supports liver function and aids in detoxification.
• Digestive Health: Used to treat constipation and promote digestive health
• Skin Health: Used for treating warts, skin infections, and other skin ailments.

Scientific Research

• Podophyllotoxin Studies: Research highlights the anticancer efficacy of podophyllotoxin in inhibiting cancer cell growth.
• Antiviral Effects: Studies show its effectiveness in treating warts caused by HPV.
• Toxicity Research: Research also indicates the toxic effects of excessive use, necessitating careful dosage.
• Sustainable Cultivation: Studies focus on propagation techniques to conserve the species in its natural habitat.